Use an advanced removal tool like or IObit Uninstaller .
Right-click the downloaded setup file and choose . 3. Clear the Windows Installer Cache
If you've tried all the solutions above and still encounter the error, contact Adobe Support with:
Once the system is cleaned, perform a fresh installation. acrosup64.dll is not marked for installation
The error "acrosup64.dll is not marked for installation" is a classic example of a Windows Installer state error. While it can be frustrating, it is rarely a sign of a virus or hardware failure. In 90% of cases, using the official to remove the corrupted install and reinstalling the software fresh will permanently resolve the issue.
Click and allow the utility to remove deep system directories and keys. Restart your computer immediately. 2. Purge Leftover Adobe Folders Manually
The problem is rarely caused by the file itself. Instead, it stems from how Windows tracks installed software: Use an advanced removal tool like or IObit Uninstaller
msiexec /unreg msiexec /regserver
Note: If AppData is hidden, select "Show hidden files, folders, and drives" in File Explorer options.
If the automated cleaner fails, a manual approach ensures no remnants are left behind. This process involves removing the physical Adobe folders and cleaning the registry. Clear the Windows Installer Cache If you've tried
This advanced technique gives you direct control over the installation process.
Open File Explorer and delete the main application directories: C:\Program Files\Adobe C:\Program Files (x86)\Adobe
: Upgrading from older versions (e.g., Reader XI) to newer versions (e.g., Acrobat DC) or reinstalling after a system crash. Root Causes Registry Conflicts : Stale entries from failed uninstalls. Leftover Files : Physical files remaining in the C:\Program Files (x86)\Adobe directories that conflict with the new installer. Installer Corruption